Field Evaluation of the Novel One Step Malaria Pf and Pf/Pv Rapid Diagnostic Tests and the Proportion of HRP-2 Gene Deletion Identified on Samples Collected in the Pwani Region, Tanzania

Summary of the Study

• This study evaluated the performance of the novel One Step Malaria Pf and Pf/Pv rapid diagnostic tests (RDTs) in the Pwani region of Tanzania.
• The study included a total of 1,845 samples collected from patients with suspected malaria.
• The results showed that the One Step Malaria Pf and Pf/Pv RDTs had a sensitivity of 97.3% and a specificity of 99.3%.
• The proportion of HRP-2 gene deletion identified on samples collected in the Pwani region was found to be 0.3%.
• The study concluded that the One Step Malaria Pf and Pf/Pv RDTs are reliable and accurate for the diagnosis of malaria in the Pwani region of Tanzania.

Detailed Overview of the Study

This study was conducted to evaluate the performance of the novel One Step Malaria Pf and Pf/Pv rapid diagnostic tests (RDTs) in the Pwani region of Tanzania. The study included a total of 1,845 samples collected from patients with suspected malaria. The samples were tested using the One Step Malaria Pf and Pf/Pv RDTs and the results were compared to the results of the gold standard microscopy. The results showed that the One Step Malaria Pf and Pf/Pv RDTs had a sensitivity of 97.3% and a specificity of 99.3%. The proportion of HRP-2 gene deletion identified on samples collected in the Pwani region was found to be 0.3%. The study concluded that the One Step Malaria Pf and Pf/Pv RDTs are reliable and accurate for the diagnosis of malaria in the Pwani region of Tanzania.

Conclusion

The results of this study showed that the novel One Step Malaria Pf and Pf/Pv RDTs are reliable and accurate for the diagnosis of malaria in the Pwani region of Tanzania. The tests had a sensitivity of 97.3% and a specificity of 99.3%, and the proportion of HRP-2 gene deletion identified on samples collected in the Pwani region was found to be 0.3%. These results suggest that the One Step Malaria Pf and Pf/Pv RDTs are a useful tool for the diagnosis of malaria in the Pwani region of Tanzania.

source of this article

published: 2023;
Field evaluation of the novel One Step Malaria Pf and Pf/Pv rapid diagnostic tests and the proportion of HRP-2 gene deletion identified on samples collected in the Pwani region, Tanzania

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