Motion lubrication suppressed mechanical activation via hydrated fibrous gene patch for tendon healing

投稿日： 2023-02-16

Motion Lubrication Suppressed Mechanical Activation via Hydrated Fibrous Gene Patch for Tendon Healing

Summary of the Study

This study aimed to investigate the effects of motion lubrication suppressed mechanical activation (MLSMA) on tendon healing.
The study used a hydrated fibrous gene patch (HFGP) to deliver genes to the tendon.
The results showed that MLSMA with HFGP improved the healing of the tendon.
The study concluded that MLSMA with HFGP is a promising approach for tendon healing.

Detailed Summary of the Study

This study aimed to investigate the effects of motion lubrication suppressed mechanical activation (MLSMA) on tendon healing. The study used a hydrated fibrous gene patch (HFGP) to deliver genes to the tendon. The HFGP was composed of a hydrated fibrous scaffold and a gene-loaded hydrogel. The hydrated fibrous scaffold was made of poly(lactic-co-glycolic acid) (PLGA) and poly(ethylene glycol) (PEG). The gene-loaded hydrogel was composed of poly(ethylene glycol) diacrylate (PEGDA) and a gene-loaded poly(ethylene glycol) (PEG).

The study used a rat model to investigate the effects of MLSMA with HFGP on tendon healing. The rats were divided into three groups: a control group, a MLSMA group, and a MLSMA with HFGP group. The rats in the MLSMA group were subjected to MLSMA, while the rats in the MLSMA with HFGP group were subjected to MLSMA and HFGP. The results showed that MLSMA with HFGP improved the healing of the tendon.

The study concluded that MLSMA with HFGP is a promising approach for tendon healing. The results showed that MLSMA with HFGP improved the healing of the tendon, suggesting that MLSMA with HFGP could be used to improve the healing of tendons. Furthermore, the study showed that MLSMA with HFGP could be used to deliver genes to the tendon, which could be used to improve the healing of the tendon. Therefore, MLSMA with HFGP could be used to improve the healing of tendons.

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Correction: Li et al. Immunogenicity of Recombinant-Deficient Lactobacillus casei with Complementary Plasmid Expressing Alanine Racemase Gene and Core Neutralizing Epitope Antigen against Porcine Epidemic Diarrhea Virus. Vaccines 2021, 9, 1084

Correction: Li et al. Immunogenicity of Recombinant-Deficient Lactobacillus casei with Complementary Plasmid Expressing Alanine Racemase Gene and Core Neutralizing Epitope Antigen against Porcine Epidemic Diarrhea Virus. Vaccines 2021, 9, 1084 Summary with Bullet Points Li et al. conducted a study to evaluate the immunogenicity of recombinant-deficient Lactobacillus casei (L. casei) with complementary plasmid expressing alanine racemase gene and core neutralizing epitope antigen against porcine epidemic diarrhea virus (PEDV). The study was conducted using a mouse model and the results showed that the recombinant-deficient L. casei with complementary plasmid expressing alanine racemase gene and core neutralizing epitope antigen induced a strong ...

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Correction: Li et al. Immunogenicity of Recombinant-Deficient Lactobacillus casei with Complementary Plasmid Expressing Alanine Racemase Gene and Core Neutralizing Epitope Antigen against Porcine Epidemic Diarrhea Virus. Vaccines 2021, 9, 1084

Summary of Li et al. Immunogenicity of Recombinant-Deficient Lactobacillus casei with Complementary Plasmid Expressing Alanine Racemase Gene and Core Neutralizing Epitope Antigen against Porcine Epidemic Diarrhea Virus. Vaccines 2021, 9, 1084 Li et al. conducted a study to evaluate the immunogenicity of recombinant-deficient Lactobacillus casei (L. casei) expressing alanine racemase gene and core neutralizing epitope antigen against porcine epidemic diarrhea virus (PEDV). The study was conducted using a mouse model and the results showed that the recombinant-deficient L. casei expressing alanine racemase gene and core neutralizing epitope antigen induced a strong immune response against PEDV. The results also showed that ...

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