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On triangle inequalities of correlation-based distances for gene expression profiles Summary of the article This paper presents a study of the triangle inequality of correlation-based distances for gene expression profiles. The authors used a dataset of gene expression profiles from the Human Genome Project to compare the triangle inequality of correlation-based distances. The authors found that the triangle inequality of correlation-based distances was violated in some cases. The authors also found that the triangle inequality of correlation-based distances was more likely to be violated when the gene expression profiles were more similar. The authors concluded that the triangle inequality of ...

On triangle inequalities of correlation-based distances for gene expression profiles Summary of the article This paper presents a study on the triangle inequalities of correlation-based distances for gene expression profiles. The authors used a dataset of gene expression profiles from the Human Genome Project to analyze the triangle inequalities of correlation-based distances. The authors found that the triangle inequalities of correlation-based distances are not always satisfied, and that the degree of violation depends on the type of gene expression profile. The authors also found that the triangle inequalities of correlation-based distances are more likely to be violated when the gene ...

Retinal determination gene networks: from biological functions to therapeutic strategies Summary of the Article Retinal determination gene networks (RDGNs) are responsible for the development of the vertebrate retina. RDGNs are composed of transcription factors, signaling molecules, and other regulatory proteins. RDGNs are essential for the formation of the vertebrate retina, and their disruption can lead to retinal diseases. Recent advances in the study of RDGNs have revealed the molecular mechanisms underlying retinal development. These findings have provided insights into the potential therapeutic strategies for retinal diseases. Molecular Mechanisms of Retinal Development Recent advances in the study of RDGNs have revealed ...

Summary of Whole Genome Sequence Analysis of the First Reported Isolate of Salmonella Agona Carrying blaCTX-M-55 Gene in Brazil The first reported isolate of Salmonella Agona carrying blaCTX-M-55 gene in Brazil was identified in a sample from a patient with gastroenteritis. Whole genome sequencing was used to analyze the isolate and compare it to other Salmonella Agona strains. The isolate was found to be closely related to other Salmonella Agona strains, but had a unique combination of genes, including the blaCTX-M-55 gene. The isolate was also found to have a number of other genes associated with antibiotic resistance, including genes ...

Summary of Whole Genome Sequence Analysis of the First Reported Isolate of Salmonella Agona Carrying blaCTX-M-55 Gene in Brazil The first reported isolate of Salmonella Agona carrying blaCTX-M-55 gene in Brazil was identified in a sample from a patient with gastroenteritis. Whole genome sequencing was used to analyze the isolate and compare it to other Salmonella Agona strains. The isolate was found to be closely related to other Salmonella Agona strains, but had a unique combination of genes, including the blaCTX-M-55 gene. The isolate was also found to have a number of other genes associated with antibiotic resistance, including genes ...

Prognosis of spontaneous pneumomediastinum occurring in dermatomyositis or polymyositis patients with interstitial lung disease according to antimelanoma differentiation-associated gene 5 antibody status: a retrospective cohort study Summary of the Study This study aimed to investigate the prognosis of spontaneous pneumomediastinum (SPM) occurring in dermatomyositis or polymyositis (DM/PM) patients with interstitial lung disease (ILD) according to antimelanoma differentiation-associated gene 5 (MDA5) antibody status. A retrospective cohort study was conducted on DM/PM patients with ILD who were admitted to the Department of Rheumatology at the First Affiliated Hospital of China Medical University between January 2011 and December 2018. The results showed that ...

Polymorphism of NOS3 gene and its association with essential hypertension in Guizhou populations of China Summary of the Study This study aimed to investigate the association between polymorphism of NOS3 gene and essential hypertension in Guizhou populations of China. A total of 545 essential hypertension patients and 545 healthy controls were recruited for the study. Genotyping of NOS3 gene was performed using PCR-RFLP method. The results showed that the frequency of NOS3 gene polymorphism was significantly higher in essential hypertension patients than in healthy controls. The study concluded that NOS3 gene polymorphism is associated with essential hypertension in Guizhou populations ...

Detection of Enterobius vermicularis in archived formalin-fixed paraffin-embedded (FFPE) appendectomy blocks: It’s potential to compare genetic variations based on mitochondrial DNA (cox1) gene Summary of the Study This study aimed to detect Enterobius vermicularis in archived formalin-fixed paraffin-embedded (FFPE) appendectomy blocks. The study used a nested PCR technique to detect the presence of E. vermicularis in the FFPE blocks. The study also used a PCR-RFLP technique to compare the genetic variations of E. vermicularis based on the mitochondrial DNA (cox1) gene. The results of the study showed that E. vermicularis was detected in the FFPE blocks. The study also showed ...

Summary of the Study This study aimed to investigate the effects of mild intermittent ketosis induced by supplementation with medium-chain triglycerides (MCTs) on reference gene expression stability in the rat brain. The study used a rat model to investigate the effects of MCTs on reference gene expression stability in the brain. The rats were divided into two groups: a control group and an MCT-supplemented group. The MCT-supplemented group was given MCTs for a period of two weeks. The results showed that MCT supplementation induced mild intermittent ketosis in the rats. The expression of the reference genes was found to be ...

Summary of RANK signaling in osteoclast precursors results in a more permissive epigenetic landscape and sexually divergent patterns of gene expression This study investigated the role of RANK signaling in osteoclast precursors and its effects on the epigenetic landscape and gene expression. The authors found that RANK signaling in osteoclast precursors results in a more permissive epigenetic landscape and sexually divergent patterns of gene expression. The authors also found that RANK signaling in osteoclast precursors results in increased expression of genes involved in osteoclastogenesis, as well as increased expression of genes involved in the regulation of bone remodeling. The authors ...