Summary of the Study
- This study aimed to investigate the effects of mild intermittent ketosis induced by supplementation with medium-chain triglycerides (MCTs) on reference gene expression stability in the rat brain.
- The study used a rat model to investigate the effects of MCTs on reference gene expression stability in the brain.
- The rats were divided into two groups: a control group and an MCT-supplemented group.
- The MCT-supplemented group was given MCTs for a period of two weeks.
- The results showed that MCT supplementation induced mild intermittent ketosis in the rats.
- The expression of the reference genes was found to be stable in the MCT-supplemented group compared to the control group.
- The results of this study suggest that MCT supplementation can induce mild intermittent ketosis in the rat brain and maintain reference gene expression stability.
Background
Ketosis is a metabolic state in which the body uses ketone bodies as an alternative energy source to glucose. Ketosis has been associated with a variety of health benefits, including improved cognitive function, weight loss, and improved metabolic health. Medium-chain triglycerides (MCTs) are a type of fat that can be used to induce ketosis. However, the effects of MCT supplementation on reference gene expression stability in the brain have not been studied.
Methods
This study used a rat model to investigate the effects of MCT supplementation on reference gene expression stability in the brain. The rats were divided into two groups: a control group and an MCT-supplemented group. The MCT-supplemented group was given MCTs for a period of two weeks. The expression of the reference genes was measured using quantitative real-time PCR.
Results
The results showed that MCT supplementation induced mild intermittent ketosis in the rats. The expression of the reference genes was found to be stable in the MCT-supplemented group compared to the control group.
Conclusion
The results of this study suggest that MCT supplementation can induce mild intermittent ketosis in the rat brain and maintain reference gene expression stability. This finding may have implications for the use of MCTs as a therapeutic intervention for neurological disorders.
source of this article
published: 2023;
Reference gene expression stability within the rat brain under mild intermittent ketosis induced by supplementation with medium-chain triglycerides
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